The nurse is caring for a postrenal transplant client taking cyclosporine (Sandimmune). The nurse notes an increase in one of the client's vital signs, and the client is complaining of a headache. Which is the vital sign that is most likely increased?

1.Pulse
2.Respirations
3.Blood pressure
4.Temperature

The vital sign that increases after taking cyclosprine is blood pressure.

Explanation:

Cyclosporine lowers your body's immune system.The immune system can also "reject" a transplanted organ such as a liver or kidney because the immune system treats the new organ as an invader.Cyclosporine is used to prevent organ rejection after a kidney, heart, or liver transplant.

In this case after a renal transplant, cyclosporine is given which is causing *Hypertension*. Hypertension usually mild to moderate, occurs in approximately 50% of patients following renal transplantation. In 10% of cases it may cause flushing, arrhythmia, purpura, abnormal heart sounds, cardiac failure, peripheral ischemia and less frequently hypertension with fluid retention and convulsions.