After gerald was diagnosed with schizophrenia, he started taking thorazine. he meets with his doctor to evaluate his progress on thioridazine. after an evaluating gerald, his doctor considers switching him from thorazine to clozaril, a drug that affects several neurotransmitters, including

serotonin

Explanation: Clozaril (clozapine) is an antipsychotic medication. It works by changing the actions of chemicals in the brain.

Clozaril is used to treat severe schizophrenia, or to reduce the risk of suicidal behavior in people with schizophrenia or similar disorders. Clozaril blocks neurotransmitters than secrete serotonin  and cause have serious side effects for example developing diabetes.

In those with schizophrenia and schizoaffective disorder it may decrease the rate of suicidal behavior. It is more effective than typical antipsychotics, particularly in those who are treatment-resistant.  It is used by mouth, or by injection into a muscle.

Clozapine is classified as an atypical antipsychotic drug because it binds to serotonin as well as dopamine receptors.

Clozapine is an antagonist at the 5-HT2A subunit of the serotonin receptor, putatively improving depression, anxiety, and the negative cognitive symptoms associated with schizophrenia.