The two most common genetic causes of intellectual disabilities are down syndrome and fetal alcohol spectrum disorder fetal alcohol spectrum disorder and tay-sachs disease down syndrome and fragile x syndrome prader-willi syndrome and pku

Down syndrome and fragile X syndrome

Explanation:

The two most common genetic causes of intellectual disability are Down syndrome and fragile X syndrome.

Fragile X syndrome is an inherited condition that determines changes in intellectual development and behavior. Although considered to be the second most common cause of genetic disability - the first being Down syndrome - the disease is poorly known, as its findings are only around 30 years old. Unlike Down syndrome which is better known and widespread.

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