The effect of a drug that is an agonist is to?

An agonist will active receptors, causing a physiological response. (Pretty much, it acts like a neurotransmitter). On the other hand, an antagonist will BLOCK a receptor, preventing a neurotransmitter from binding on that receptor, therefore blocking a physiological response.
Agonist --> acts like a neurotransmitter and elicits a responseAntagonist --> BLOCKS a neurotransmitter by binding on to the receptor, therefore blocking a response.

Cacium and phosphous build strong and flaxble bones. a diet that lacks these nutrients can lead to osteoprosis should be it hopefully