Which acts as both a physical and chemical barrier against pathogens? blood skin lymph mucus

Skin

The first line of defense against any pathogen attempting to invade the body is your skin.  The largest organ of your body can physically prevent invaders from getting inside and can also chemically change them by methods such as sweat and desiccation.  

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note: for words found inappropriate, i spelled them out in the phonetic alphabet in parenthesis, so take the first letter of each word to get the word i was trying to spell

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