Compare and contrast the medical technology from 1800s to present day

There wasn't many vaccinations back in the day and medicine slowly developed through years passing by. Also eras such as the Black plague and others really helped develop medicines and vaccinations moving forward for people to use. 
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The answer to this question is  c. pharmaceutical accumulation  reclaimed water refers to the water that being used again after it already  used for agricultural purposes.this type of water often contains pharmaceutical accumulation because of the chemical fertilizer that is used for the plants is absorbed into the water.

Maybe a horizontal because its a pattern