After contact with the europeans in the 1500s millions of native people did what

Well there are multiple answers. the Native Americans were forced to covert to Christianity or else they would die. Many to all were put to work as slaves too. Poor work conditions and diseases led to the decline of the Native American colonies. They also died and lost a huge population due to battling the Europeans that arrived in high quality armor and weapons, along with horses. even though the Europeans were outnumbered, they defeated the Native Americans due to te advantages they had.

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