A plausible inference is supported by evidence in the article 35 million and counting and is considered with known fact outside of the article

The investiture controversy began as a power struggle between pope gregory vii (1072–85) and henry iv, holy roman emperor (1056–1106).[2] a brief but significant struggle over investiture also occurred between henry i of england and pope paschal ii in the years 1103 to 1107, and the issue played a minor role in the struggles between church and state in france, as well.by undercutting the imperial power established by the salian emperors, the controversy led to nearly 50 years of civil war in germany, and the triumph of the great dukes and abbots. imperial power was finally re-established under the hohenstaufen dynasty. historian norman cantor:

The answer to this question is  c. pharmaceutical accumulation  reclaimed water refers to the water that being used again after it already  used for agricultural purposes.this type of water often contains pharmaceutical accumulation because of the chemical fertilizer that is used for the plants is absorbed into the water.