What is the difference between a fable and a satire?

A fable is not a real story, usually a fable contains a moral tale. Example - the scorpion and the frog.
A satire uses humor, an irony to ridicule people- talks about politics and major topics. An example of Satire is Bill, Maher.

.A fable states the moral or lesson directly, while a satire often disguises the main argument.