Where should a comma be placed in this sentence? kari and misha, who have known each other since first grade are both yearbook editors and photographers.

The answer to your question would be that in the sentence above a comma should be placed after "first grade". That is, the sentence would be as follows: Kari and Misha, who have known each other since first grade, are both yearbook editors and photographers.

"Who have known each other since first grade" is a nonessential relative clause. A nonessential relative clause is one that is not necessary. Consequently, the clause can be removed from the sentence without altering the sentence's meaning. When a sentence has a nonessential relative clause, the clause is set apart with commas.

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i think the answer is d.