Chemistry, 12.12.2021 14:00, daisylaloca

Angiotensin II is an octapeptide that is used to treat hypotension resulting from septic shock or other distributive shocks. Questions
1. Assess the purity of Angiotensin II using Polyacrylamide Gel Electrophoresis (PAGE)
2. The amino acid analysis gives (Ile, Phe, Pro, Arg, Asp, His, Tyr, Val). Partial hydrolysis gives five fragments, which are sequenced by several cycles of Edman degradation as: Pro-Phe, Ile-His-Pro, Arg-Val-Tyr, Asp-Arg-Val, Val-Tyr-Ile What is the sequence?

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Angiotensin II is an octapeptide that is used to treat hypotension resulting from septic shock or ot...