Amantadine is effective in preventing infections caused by the influenza A virus and in treating established illness. It is thought to block a late stage in the assembly of the virus. Amantadine is synthesized by treating 1-bromoadamantane with acetonitrile in sulfuric acid to give N-adamantylacetamide, which is then converted to amantadine. Draw curved arrows to show the movement of electrons in this step of the reaction mechanism.
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