What is Williamson's synthesis?

The Williamson ether synthesis is an organic reaction, forming an ether from an organohalide and a deprotonated alcohol. This reaction was developed by Alexander Williamson in 1850. Typically it involves the reaction of an alkoxide ion with a primary alkyl halide via an SN2 reaction.

The name of the reaction was coined after Alexander William Williamson developed it in 1850.Williamson Ether Synthesis is a reaction that uses deprotonated alcohol and an organohalide to form an ether. 1. Williamson Ether Synthesis usually takes place as an SN2 reaction of a primary alkyl halide with an alkoxide ion.

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