Chemistry, 22.04.2020 15:59, Roberto2014
It is difficult to prepare an amide from a carboxylic acid and an amine directly, since an acid-base reaction occurs which renders the amine nitrogen non-nucleophilic. Typically, in such an amide synthesis, the carboxylic acid OH group is first transformed into a better, nonacidic leaving group. In practice, amides are often prepared by treating the carboxylic acid with dicyclohexylcarbodiimide (DCC). The amine is then added and nucleophilic acyl substitution occurs easily because dicyclohexylurea is a good leaving group. This method of amide bond formation is a key step in the laboratory synthesis of peptide bonds (amide bonds) between protected amino acids. Draw curved arrows to show the movement of electrons in this step of the mechanism.
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Chemistry, 22.06.2019 09:00, lrasanaoaksandfurana
Which process does not require the presence of a physical substance in order to transfer heat? air in the atmosphere is heated by the ground. this warm air then rises, and cooler air falls. this is an example of what type of process? how is conduction different from radiation?
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Chemistry, 22.06.2019 14:30, lorrainelopez
The three types is stress that act on earths rocks are compression, tension, and
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It is difficult to prepare an amide from a carboxylic acid and an amine directly, since an acid-base...
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