Chemistry, 12.02.2020 21:06, kedjenpierrelouis

For a mutant in which the T-R equilibrium is shifted toward the R state, what type of change would you expect in P50? (Would the P50 for the mutant be higher or lower than normal HbA?) Does that mean O2 affinity of mutant is higher or lower than normal? Sketch a normal HbA binding curve (sigmoid) and then sketch the curve you would expect for a mutant with T-R equilibrium shifted toward the R state.

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For a mutant in which the T-R equilibrium is shifted toward the R state, what type of change would y...