Let’s quantify this ^ binding equilibrium to answer some general questions: does l bind to p tightly with high affinity, or weakly with low affinity? how much ligand is required to saturate the binding site to a certain %?

a electronegativity decreases beacuse the size of nucleus is bigger.

definition

                    entropy is a measure of the randomness or the extent of disorder of a chemical process.

                      enthalpy is a measure of the heat change of a reaction occurring at a constant pressure.

measurement units:

                        entropy is measured in joule per kelvin (jk⁻¹)   whereas enthalpy is measured in joule per mole (jmol⁻¹)

requirements:

                            entropy has no requirements or limits, and its change is measured by the division between the heat change of the chemical process and the temperature.

                              in contrast, enthalpy can only be related to the heat change of the reaction under standard conditions.