Adeficiency in thiamine (tpp) will directly decrease the activity of which of the following enzymes? a. pyruvate carboxylase b. glucose 6-phosphate dehydrogenase c. aldolase bd. transketolase

d. Transketolase

Explanation:

Transketolase utilize thiamine diphosphate (ThDP) as cofactor has reduced activity during the thiamine deficiency and results in the tissue damage. The levels of steady-state mRNA of transketolase in human lymphoblasts, fibroblasts and neuroblastoma cells are found to be lower in the thiamine-deficient cultures.  

Thus, deficiency in TPP directly decrease the activity of enzyme, transketolase.

in 1783 cavendish was working with his hydrogen gas and found that when he burned it and condensed the vapor it was water. this was very significant since it disproved the greek theory of elements completely since water was not a simple substance but the product of two gases. it was lavoisier who hearing of the experiment gave cavendish's gas the name hydrogen ("water-producer") and added that hydrogen burned by combining with oxygen and that water was a hydrogen-oxygen combination.

explanation: