Chemistry, 05.07.2019 20:20, naansah52631

Apatient enters the emergency room (e. r.) and needs an infusion of acetaminophen to achieve a steady-state concentration of 5.0 mg/l in his bloodstream. the volume of distribution of acetaminophen is 63 l. acetaminophen can be considered to be eliminated entirely by metabolism in the liver, with a first-order elimination rate constant ke 0.35 h a) find the infusion rate of acetaminophen in mg/min the patient returns home, but eventually the pain returns. therefore, the patient takes a 500 mg pill of acetaminophen. acetaminophen is absorbed by the gl tract via a first order process with a rate constant k 2.2 h1. b) at what time is the maximum acetaminophen concentration reached and what is the maximum concentration? assume that the initial concentration of acetaminophen is zero. c) if the patient has liver disease, causing a reduction in the elimination kinetics, sketch what will be the effect on the concentration vs. time profile and explain your for the infusion case of part (a) for the pill absorption case of part (b) a. b. d) acetaminophen freely crosses the blood-brain barrier. how does the concentration vs. time profile in the brain compare with that in the bloodstream?

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Apatient enters the emergency room (e. r.) and needs an infusion of acetaminophen to achieve a stead...