How does the shape of an enzyme affect its function?

Each enzyme's active site is suitable for one specific type of substrate – just like a lock that has the right shape for only one specific key. Changing the shape of the active site of an enzyme will cause its reaction to slow down until the shape has changed so much that the substrate no longer fits.

the answer is 1 i believe

aquifers are bounded above and below by impermeable rock. the driving force of groundwater movement in confined aquifers is pressure, rather than gravity.