Caffeine molecules are large. do you think caffeine molecules can easily pass into a cell? why or why not?

Yes, caffein molecules can easily pass into a cell.

Caffeine is a chief ingredient of tea and coffee. When a person drinks tea or coffee the caffeine is carried along the bloodstream and transferred to all the cells in the body. Caffeine molecules although large but they are soluble in the body fat. This fat solubility ensures the passage of caffeine through the cell membrane. It is readily absorbed by the stomach and intestine and then to blood stream, and then blood carries it to other organs of the body. It permeates to all organs of the body, faster than other drugs but slower than alcohol. It receives no physiological barrier which can prevent the passage through tissues in the body. Therefore, the concentration of caffeine remains virtually the same throughout all the bodily fluids like blood, semen, saliva and breast milk.

the positions which points up in upward carbon and down in downward carbon are axial

and vice versa holds true for equatorial positions

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