Biology

Biology, 31.07.2019 12:30, jaceechesick

He human gene egfr located on chromosome 7 is a proto-oncogene that codes for a growth factor cell surface receptor. the binding of growth factors to this receptor can lead to cell proliferation. hypothesize what potential impact a mutated egfr allele will have on a cell. give one possible impact and explain your answer

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Biology, 19.07.2019 00:10, Fauxfox

Determine if each description below applies to an oncogene, a proto-oncogene, or a tumor suppressor gene. some descriptions may apply to more than one of these gene types. drag the gene types on the left to the appropriate blanks on the right to match the descriptions. gene types can be used once, more than once, or not at all. - gene(s) that could code for a normal growth factor. - gene(s) whose presence can cause cancer. - type of gene(s) found in normal cells and cancer cells. - type of gene(s) found in cancer cells. - type of gene(s) found only in cancer cells. - gene(s) whose absence can cause cancer. - type of gene(s) found in normal cells.

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Biology, 20.07.2019 12:30, edwinn55526

The association constant, ka, of epithelial growth factor receptor (egfr) binding to epithelial growth factor (egf) is 5.61 x 106. what is the keq of egfr + egf → egfr-egf?

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Biology, 09.10.2019 16:30, deanlmartin

Density-dependent inhibition is a phenomenon in which crowded cells stop dividing at some optimal density and location. this phenomenon involves binding of a cell-surface protein to its counterpart on an adjoining cell's surface. a growth inhibiting signal is sent to both cells, preventing them from dividing. certain external physical factors can affect this inhibition mechanism.select the statement that makes a correct prediction about natural phenomena that could occur during the cell cycle to prevent cell growth.a) as cells become more numerous, they begin to squeeze against each other, restricting their size and ability to allow cell growth.b) as cells become more numerous, the protein kinases they produce begin to compete with each other until only one cell has the proteins necessary for growth.c) as cells become more numerous, the amount of required growth factors and nutrients per cell becomes insufficient to allow for cell growth.d) as cells become more numerous, more and more of them enter the synthesis part of the cell cycle and duplicate dna to inhibit cell growth.

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Health, 15.10.2019 19:20, sidemen10117

The primary amino acid sequence of the epidermal growth factor receptor (egfr) contains an invariant lysine amino acid essential for kinase activity. substitution of this essential lysine by any other amino acid blocks the capacity of the receptor to phosphorylate targets. what stage of receptor activation is disrupted by substitution of the invariant lysine with another amino acid? when this lysine is replaced by another amino acid: a) egfr is unable to activate an associated trimeric g-protein. b) the ligand epidermal growth factor (egf) is unable to bind to egfr. c) docking sites for egfr target proteins are not generated inside the cell. d) egfr becomes constitutively activated, that is, egfr is always on. e) enzymatically inactive egfr monomers are unable to dimerize.

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