In single-gene traits, natural selection can lead to which of the following?
a. allele frequency change
b. directional selection
c. disruptive selection
d. founder effect

Answer;

-Allele frequency change

In single-gene traits, natural selection can lead to allele frequency change.

Explanation;

-Allele frequencies can change over time within a single population, and frequently differ between populations. This change is due to four different processes: mutation, selection (natural and artificial), gene flow and genetic drift.

-Random forces lead to genetic drift. Sometimes, there can be random fluctuations in the numbers of alleles in a population. These changes in relative allele frequency, called genetic drift, can either increase or decrease by chance over time.

c.) polymerase chain reaction

- "unlike the original dna fingerprinting method, dna profiling does not use restriction enzymes to cut the dna. instead it uses the polymerase chain reaction (pcr)? to produce many copies of specific str sequences. pcr is an automated procedure that generates lots of copies of a specific sequence of dna."

true, i don't really know what you're asking but from the info you provided im guessing the answer is true.