James has been diagnosed with cluster headaches. appropriate acute therapy would be:

James should be given an Oxygen 100% for 15 to 30 minutes.  Preventative therapy for cluster headaches includes Ergotamine nightly before bed. Cluster headaches are a series of relatively short but extremely painful headaches every day for weeks or months at a time. You tend to get them at the same time each year, such as the spring or fall. Because of their seasonal nature, people often mistake cluster headaches for symptoms of allergies or business stress.

answer: - b cells

explanation: -

so, the b cells mediate their action by identifying the antigens present on the surface of the pathogens and then producing antibodies in return to mediate its effect.

i think its the first one