All animals that swim freely in the ocean are known

I’m doing some practice exam questions for biology, and i’m not sure how to do these 3 parts to the question.

Predict the results of a two base insertion or deletion in a strand of dna that codes for a protien, how does this differ from a three base insertion or deletion?

Which two factors contributed to creating a global culture? the creation of the united nations improvement in telecommunications health issues such as the ebola virus increased opportunities for global travel