What poses a great threat to the entire human species; poisonous abiotic factors or poisonous biotic factors?

Well, biotic factors are living things in an ecosystem such as animals or insects. Abiotic factors are non living things in an ecosystem such as sunlight or temperature. I would say biotic factors would be more harmful since this includes bacteria or other diseases, not many abiotic factors would pose a great threat to the entire human species. Hope this helped.