Positive transcription factor (PTR) is important because it turns genes on to prepare them to be read. What is more important (i. e., which has a greater impact if it is changed): concentration or affinity? If PTR concentration is low but affinity is high, then what will happen to protein levels versus if PTR affinity is high but concentration is low? Argue your point in three to five sentences. Use the simulation if necessary. Please Help! (30 pts)

Transcription factors are vital molecules in the control of gene expression, directly controlling when, where and the degree to which genes are expressed. They bind to specific sequences of DNA and control the transcription of DNA into mRNA. Gene regulation is an important part of normal development. Genes are turned on and off in different patterns during development to make a brain cell look and act different from a liver cell or a muscle cell.

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