Which of the following would be a good chemotherapy approach: blocking formation of the ribonucleotide ATP or blocking formation of the deoxyribonucleotide dATP? Why? Please explain the chemical differences between each of the two nucleotides and tell how each is important to cellular function (i. e. give 3 general processes for ATP and 1 for dATP). In addition, use the specific processes below to support your choice by explaining how either ATP or dATP are related to these and how loss of the particular molecule would affect each process.
A) Activation of glucose in glycolysis.
B) Formation of carbamoyl phosphate in the Urea Cycle.
C) Activation of a fatty acid in ß-oxidation.