Regarding the models of cooperativity:. a. the concerted model is based on the
b. T state and the sequential on the R state.
c. T state is low affinity and R state is high affinity.
d. the concerted model and the sequential model are mutually exclusive.
e. these models, strictly speaking, only apply to tetramers.

c. T state is low affinity and R state is high affinity.

Explanation:

Hemoglobin (Hb) is a multimeric protein molecule that transports oxygen from the lungs to the body's tissues in red blood cells. Hb exists in two quaternary states: 1- a T-state or deoxygenated conformation, which is referred to as 'deoxyhemoglobin'; and 2-a R state or fully oxygenated conformation, which is referred to as 'oxyhemoglobin'. The sequential model of cooperativity states that the conformation of a multimeric protein changes with each binding of a ligand, thereby sequentially changing its affinity for the ligand (i.e., cooperativity is dependent on ligand-induced). In consequence, this model states that the conformational state and affinity of Hb monomers change as they bind to oxygen.

cellular respiration oxidizes food into energy in the form of atps.

glycolysis (6 c hexose) > 2x atps are used > 6c hexose biphosphate > 2 x 3c triphosphate >

2 x 3c pyruvate (2x nadh produced from nad) and (4x atp produced)

pyruvate actively pumped mitochondrial matrix.