You wish to develop a monoclonal antibody (mAb) that binds with high affinity to the SARS-CoV-2 spike (S) protein, for use as a therapeutic agent. You have isolated a human B-cell clone that produces an IgG that is specific for the SARS-CoV-2 S protein, but its affinity for binding the target epitope is low. Describe in conceptual detail how you could use a protein engineering approach to enhance the affinity of the mAb for the target antigen.​

In german cockroaches, curved wing (cv) is recessive to normal wing (cv+). bill, who is raising cockroaches in his dorm room, finds that the frequency of the gene for curved wings in his cockroach population is 0.6. in his friend joe’s apartment, the frequency of the gene for curved wings is 0.2. one day joe visits bill in his dorm room, and several cockroaches jump out of joe’s hair and join the population in bill’s room. bill estimates that, now, 10% of the cockroaches in his dorm room are individual roaches that jumped out of joe’s hair. what is the new frequency of curved wings among cockroaches in bill’s room? 0.69 0.4 0.5 0.31 0.20

Guinea pig coat color is determined by a single gene. the allele for black coat color is dominant to brown. in a cross between twoblack-haired guinea pigs, 20 offspring are born. if both parents were heterozygous, probability would predict that approximately howmany of the 20 offspring would have brown hair?

The pie chart tracks the percentage of renewable energy that's being used in a particular community near the ocean. what are two advantages of using this type of graph for this particular data set?