How can increased androgens lead to negative feedback inhibition of the pituitary?

The seaport that is near caracas has which type of climate?

Which mantle is under the crust the upper mantle or the lower mantle i think it's upper let me know if i'm right

Amylase becomes denatured at a temperature of 80°c. during an experiment to study the effect of varyingtemperature on enzyme activity, amylase’s reactivity with starch was measured at body temperature (37°c), andthen again at an increased temperature of 42°c. how would this increase in temperature affect the experiment