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The most common Class II variant is the F508del variant, which is missing the 508th amino acid in the protein but has an otherwise normal sequence. Loss of this amino acid leads to misfolding of the protein, and the misfolded protein is not properly transported to the membrane. Based on this information, how many nucleotides are deleted in the CFTR allele encoding this variant?
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The most common Class II variant is the F508del variant, which is missing the 508th amino acid in th...
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