Biology, 23.06.2021 07:10, MrTeriffic

Sickle cell anaemia is an inherited autosomal recessive condition caused by a mutation in the haemoglobin
subunit beta (HBB) gene. A male and female who are
phenotypically normal, discover through genetic testing
that they are both carriers of a HBB mutant allele. What is
the probability that their first child will be biologically
female and phenotypically normal?

Answers: 3

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Answers

answered: sheila101

1/8 (12.5%)

Explanation:

An autosomal recessive disease is an inherited disease in which an individual need to receive both defective alleles at the same gene locus to be expressed in the phenotype. In this case, both parents are carriers of the recessive mutant allele associated with the sickle cell anaemia trait, thereby both parents are heterozygous, ie., each parent has one copy of the normal allele 'H' and one copy of the defective mutant allele 'h' associated with this condition. In consequence, their first child has a 1/4 (25%) chance of having sickle-cell anaemia. Moreover, the chance of having a girl is 1/2 and the chance of having a boy is 1/2, thereby the final chance of having a girl sickle cell anaemia individual is 1/4 x 1/2 = 1/8 (12.5%).

- Parental cross for sickle cell anaemia trait = Hh x Hh >>

- F1 = 1/4 HH (normal); 1/2 Hh (normal); 1/4 hh (sickle cell anaemia) >>

- Sex proportion of sickle cell anaemia individuals = 1/8 female sickle cell anaemia individuals + 1/8 male sickle cell anaemia individuals (1/8 + 1/8 = 1/4)

answered: Guest

answer: if she breaths she a thho

explanation:

answered: Guest

Mantle convection is the slow creepingmotion of earth's solid silicate mantle caused by convection currents carrying heat from the interior to the planet's surface.[1][2] the earth's surface lithosphere, which rides atop the asthenosphere (the two components of the upper mantle), is divided into a number of plates that are continuously being created and consumed at their opposite plate boundaries. accretion occurs as mantle is added to the growing edges of a plate, associated with seafloor spreading. this hot added material cools down by conduction and convection of heat. at the consumption edges of the plate, the material has thermally contracted to become dense, and it sinks under its own weight in the process of subduction usually at an ocean trench.[3]this subducted material sinks through the earth's interior. some subducted material appears to reach the lower mantle,[4] while in other regions, this material is impeded from sinking further, possibly due to a phase transition from spinel to silicate perovskiteand magnesiowustite, an endothermic reaction.[5]the subducted oceanic crust triggers volcanism, although the basic mechanisms are varied. volcanism may occur due to processes that add buoyancy to partially melted mantle causing an upward flow due to a decrease in density of the partial melt.secondary forms of convection that may result in surface volcanism are postulated to occur as a consequence of intraplate extension[6] and mantle plumes.[7]it is because the mantle can convect that the tectonic plates are able to move around the earth's surface.[8]mantle convection seems to have been much more active during the hadean period, resulting in gravitational sorting of heavier molten iron, and nickel elements and sulphides in the core, and lighter silicate minerals in the mantle.