What are the features of EGFR Gene Editing? EGFR is a recognized regulator of the oncogenic phenotype. Overexpression of EGFR has been reported and implicated in the pathogenesis of many human malignancies including lung cancer, head and neck, bladder cancer, ovarian cancer, and cervical cancer. Some studies have reported that EGFR overexpression is associated with advanced disease, poor chemosensitivity, and prognosis. In view of the functional involvement of EGFR in a variety of cellular processes, several approaches targeting and interfering with EGFR-mediated have been developed.

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Is snow a type of precipitation? explain why or why not.

Match the descriptions / definitions with the term they best describe 1. three dimensional relationship of the different polypeptide chains in a multisubunit protein or protein complex 2. common folding pattern in proteins in which a linear sequence of amino acids folds into a right-handed coil stabilized by internal hydrogen-bonding between polypeptide backbone atoms. 3. the amino acid sequence of a protein 4. a region on the surface of a protein that can interact with another molecule through noncovalent bonding. 5. three-dimensional arrangement of alpha-helices and beta-sheets within a single polypeptide, typically stabilized by a variety of noncovalent bonds, including ionic and hydrogen bonds, and nonpolar interactions / hydrophobic force. 6. the chain of repeating carbon and nitrogen atoms, linked by peptide bonds, in a protein. 7. common structural motif in proteins in which different sections of the polypeptide chain run alongside each other and are joined together by hydrogen bonding between atoms of the polypeptide backbone. 8. portion of a polypeptide chain that has a discrete tertiary structure of its own and can often fold independently of the rest of the chain 9. regular local folding patterns in a protein, including alpha-helix and beta-sheet a. primary structure b. beta-sheet c. protein d. coiled-coil e. polypeptide backbone f. secondary structure g. side chain h. tertiary structure i. binding site j. alpha-helix k. quaternary structure l. protein domain

Aboy with an extra x chromosome probably has which of the following syndromes?