Aminoacyl-tRNA synthetase is an enzyme that is responsible for attaching the correct amino acid to the tRNA molecule. As the mRNA transcript is read by the ribosome, the complementary tRNA molecule then brings the
correct amino acid to the polypeptide chain. Although aminoacyl-tRNA synthetase is very accurate, it will rarely
attach the wrong amino acid to the tRNA. Which of the following could be the cause of an error in this process
that results in the histidine amino acid being substituted for a phenylalanine amino acid, causing a misfolding of
polypeptide chain?
The wobble effect of RNA will allow aminoacyl-tRNA synthetase to bind to a group of amino acids.
Aminoacyl-tRNA synthetase will change the structure of the tRNA to allow for binding to a different amino acid.
O Certain amino acids have very similar structures in their attachment ends and can cause aminoacyl-tRNA
synthetase to bind to the wrong amino acid.
O Aminoacyl-tRNA synthetase determines if a misreading error has occurred by the ribosome and will replace the
tRNA anticodon to pair with a different amino acid.