On the planet Kermit, in the Muppet population, there are two autosomal loci of interest. The first locus has alleles A and a, and the second locus has alleles B and b. A and B are the dominant alleles at the respective loci. The loci act in an epistatic manner, identical to the way two genes interact to produce coat color in labradors. The phenotype here is muppet hair color. We have the following results: Muppet hair color as a function of two-locus genotypes

Two-locus genotype Muppet hair color
A_B_ Cookie monster blue
aaB_ Elmo red
__bb Janice blonde

If two doubly-heterozygous Cookie-monster blue-haired muppets mate, and produce 1000 children, which of the follow values most closely represents the expected number of Janice blonde-haired offspring?

a. 12.
b. 260.
c. 252.
d. 512.
e. 240.

Penicillin is hydrolyzed and thereby rendered inactive by penicillinase (also known as β-lactamase), an enzyme present in some resistant bacteria. the mass of this enzyme in staphylococcus aureus is 29.6 kd. the amount of penicillin hydrolyzed in 1 minute in a 10-ml solution containing 10-9 g of purified penicillinase was measured as a function of the concentration of penicillin. assume that the concentration of penicillin does not change appreciably during the assay. penicillin(μm) amount hydrolyzed(nmol) 1 0.11 3 0.25 5 0.34 10 0.45 30 0.58 50 0.61 (a) plot v0 versus [s] and 1/v0 versus 1/[s] for these data. does penicillinase appear to obey michaelis-menten kinetics? if so, what is the value of km? (b) what is the value of vmax? (c) what is the turnover number of penicillinase under these experimental conditions? assume one active site per enzyme molecule.