The welwitindolinones are a unique class of natural products isolated from the blue-green algae with cancer fighting properties. Journal of the American Chemical Society2014136(42), 14710-14713 Below is one portionof the synthetic transformation. Provide the mechanism of actionfor both products. Justify the formation of intermediatesformed during thecourse of the mechanismandprovide alterative reagents to accomplish the same transformationconcerning the nucleophilic intermediate thatclosesthe ring (6 points)

Cold case files recently began re-investigating an old murder case. the murder took place in the park; a young man, james, was hit over the head with a brick and killed. police suspected the jealous former boyfriend of james' wife, karen. whoever killed james may have washed their hands in a near-by bird bath as detectives found blood in the bird bath. since the murder took place before dna fingerprinting was available, the suspected killer, ronnie, went free. detectives are now reviewing the blood evidence using dna fingerprinting. based on the dna fingerprints of all possible suspects, who is james' killer?