Ahigh fever causes an enzyme to lose its three dimensional structure and function. which bonds are broken when a protein denatures?

The appropriate response is hydrogen bonds. Fever is an adjust of gainful and destructive impacts. High fevers can have a tendency to skew the adjust toward the destructive. 
The reality of the matter is that protein optional structure (generally hydrogen bonds) start to denature when moving toward 41 degC (106 degF), however energy likewise change. Energy is a quite major ordeal, even a little temperature move can altogether affect the speed of a response or connection.

Maybe haha