Several types of mutations can occur in cells. however, very few of these mutations develop into malignant cancerous tumors because
the benign cells are more dangerous and more common
the mutation must cause a non-disjunction that develops a syndrome
the mutation must be dramatic single point insertion or deletion
the mutation must occur in a specific gene that controls cell division

Option). the mutation must occur in a specific gene that controls cell division.

Explanation:

Mutations can be defined as permanent alterations in genetic material due to changes in sequence of DNA. Mutations may be random or induced due to exposure of cancer-causing chemicals.

Malignant cells are tumor-forming cells that show uncontrolled grow and division. These cells are formed by loss of control of cell division and bypass normal cell death.

There are several types of mutations that take place in a cell, but only few mutations cause formation of malignant cells. This is because, to be develop into a malignant, mutations must take place in genes that regulate cell division.

Thus, the correct answer is last option.