Which of the following does not play a role in determining whether individuals get cancer from a carcinogen?

1.their genetic makeup

2.how much of the carcinogen they are exposed to

3.their sex chromomes, or gender

4.how long they are exposed to a carcinogen

The correct answer is 3.
The sex hormones, or gender, would not be able to discriminate the occurrence of cancer, due to exposure to a carcinogen.
Gender may affect in the cases when the cancer is hereditary, and it sex-linked. 
Otherwise, in non-hereditary cancers, the gender and sex hormones will not affect the chances of getting cancer.

Very minute and important evidence needs to be collected in order together detail and figure out what had happened