How is mitochondrial dna (mtdna) typing used in forensic science? an unknown mtdna sample is matched to a sample of nuclear dna that was found at a crime scene. an unknown mtdna sample is matched to a sample of mtdna that was found at a crime scene. an unknown nuclear dna sample is matched to a sample of nuclear dna that was found at a crime scene. an unknown nuclear dna sample is matched to a sample of mtdna that was found at a crime scene..