Describe the characteristics of the keratinocyte membrane that restrict water movement across the membrane. If isolated keratinocytes are placed in a hypotonic solution for 24 hours, explain why there are likely to be far fewer cells at the end of this time than there were at the start.

It has four layers and attach with each other with desmosome.

Explanation:

The keratinocytes are arranged in four different layers which are the stratum basale, stratum spinosum, stratum granulosum, and stratum corneum. These cells are attached with desmosome which is a membrane protein. The presence of these four layers made a barrier against damage done by heat, UV radiation, water loss, pathogens etc. There are fewer cells at the end of the time as compared to the start because may be of the water pressure on the membrane or these cells for a long time.