Plasmids are circular DNA found in bacteria that harbor a small number of genes for particular functions. They can be populated among bacteria cells and give rise to such properties as drug resistance or the ability to cause clinically morbid conditions (virulence). The bacteria Klebsiella pneumoniae (Kp) is a pathogen that causes pneumonia. A recent outbreak of pneumonia was caused by strains of Kp containing mosaic plasmids that carried both multi-drug resistant (MDR) and virulence genes, which are commonly found on different plasmids in previously isolated bacteria clones. Experts warned that the newly identified Kp strains with both MDR and virulence determinants posed high risks to public health. Required:
What is the negative consequence of having Kp strains with both drug-resistance and virulence-determining elements?