Generalize: Another chromosomal disorder, called Edward’s syndrome, occurs when a person’s cells have three copies of chromosome 18. People who have Edward’s syndrome have severe intellectual disabilities and their skeletons are malformed. Most people with Edward’s syndrome die in infancy. Use the above information about Edward’s syndrome and the descriptions of Down syndrome, Klinefelter syndrome, and Turner syndrome in the table on the previous page to compare these four different chromosomal disorders.

A. Which type of chromosomal disorders seems to have the greatest affect on a person’s health—disorders involving autosomes or sex chromosomes?

B. Why do you think this might be the case?