(AKS 5a/DOK 2) According to Chargoff's Rule, if a DNA strand has 30% guanine before semi-conservative replication occurs, what percentage of thymine will each new strand have after replication?
A. 20%
B. 60%
C. 40%
D. 30%

According to Chargaff's rule, if a DNA strand has 30% guanine before to semi-conservative replication, the  percentage of thymine that will have each new strand after replication will be 20% (option A).

Explanation:

A DNA molecule stores the genome of a living organism in a specific sequence of its nitrogenous bases adenine, guanine, cytosine and thymine. By knowing the percentage of a nitrogenous base in the DNA, the percentage of the other bases can be established using Chargaff's base pair rule.

Chargaff was able to establish that in a DNA molecule the ratio purine:pyrimidine is 1:1, so there must be the same amount of guanine as cytosine and a similar amount of adenine for thymine, taking into account the complementarity of the bases.

According to the base pair rule, if in a DNA strand there is 30% guanine, in the molecule there is:

In this case, Chargaff's rule is useful to determine the percentage of thymine that each new strand will have after replication, corresponding to 20%.

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