The rate limiting reaction of aerobic respiration involves the phosphorylation of by the enzyme . The rate at which this enzyme makes product is when ATP levels rise because the molecule binds to an site on the enzyme and acts as a(n) . When ATP levels fall binds to of . This interaction leads to an increase of cellular , so that this is a n example of a feedback loop.

Explanation:

The rate limiting reaction of aerobic respiration involves the phosphorylation of fructose phosphate by the enzyme phosphofructokinase. The rate at which this enzyme makes product is [increased, decreased] when ATP levels rise because the molecule ATP binds to an allosteric site on the enzyme and acts as a direct inhibitor. When ATP levels fall AMP binds to the allosteric site of phosphofructokinase. This interaction leads to an increase of cellular ATP, so that this is an example of a negative feedback loop.