When would you find the DNA not as tightly coiled? Why?

Each chromosome within a cell has its own strand of DNA. So with 23 pairs of human chromosomes, every human cell should host 46 strands of DNA — each wrapped around hundreds of thousands of histones. This tight coiling helps the body to pack its long DNA molecules into very tiny spaces.

Explanation:

Hope this helps! if so! ^^

cancer   is   essentially   uncontrolled   mitosis   of specialized cells

poor water quality affects most estuarine organisms, including commercially important fish and shellfish. the pollutants that have the greatest impact on the health of estuaries include toxic substances like chemicals and heavy metals, nutrient pollution (or eutrophication), and pathogens such as bacteria or viruses.