Given the roles of NAD /NADHNAD /NADH in dehydrogenation reactions and NADPH/NADP NADPH/NADP in reductions, would you expect the intracellular ratio of NAD /NADHNAD /NADH to be high or low? what about the ratio of NADP + to NADPH? Explain.

The correct answer would be - high intercellular ratio the ratio of NAD/NADH and low intercellular ratio the ratio of [NADP+]/[NADPH]

Explanation:

The role of NAD/NADH in dehydrogenation reactions and NADPH/NADP  in reductions explains that to promote or increase the oxidation of substrates the ration of NAD+/NADH should be high:

malate + NAD+ <===-> OAA +NADH + H+.

As NADPH and NADP+ generally help to increase the reduction of substrates, so we expect the ratio of [NADP+]/[NADPH] to low.

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