Biology, 09.12.2020 21:50, guazet7650
When epidermal growth factor (EGF)—the ligand for the epidermal growth factor receptor (EGFR)—binds EGFR on the cell surface, the intracellular domain of the receptor changes shape into an "active state.” The receptor then induces a cascade of kinases in the cytoplasm, resulting in the activation of mitogen-activated protein kinase (MAPK). One effect of EGFR signaling is the stimulation of cell proliferation. Overactive EGFR is frequently found in cancer cells.
PLEASE HELP QUICK
One strategy for developing anticancer drugs is to target the overactive signaling proteins found in cancer cells. Antibodies are proteins made by immune cells that only recognize specific biomolecules, called antigens. The major component of an anticancer drug is an antibody that specifically recognizes and binds EGFR.
Which of the following will most likely happen when this anticancer drug is applied to a tumor that has a high level of EGFR?
A) Tumor cells with active EGFR will increase and MAPK activity in the tumor will increase.
B)Tumor cells with active EGFR will decrease and MAPK activity in the tumor will increase.
C) Tumor cells with active EGFR will increase and MAPK activity in the tumor will decrease.
D) Tumor cells with active EGFR will decrease and MAPK activity in the tumor will decrease.
Answers: 2
Biology, 22.06.2019 13:00, dianelys3083p5spb5
Which of the following cell structures is significantly different between gram- positive and gram-negative bacteria?
Answers: 3
Biology, 22.06.2019 16:30, officialrogerfp3gf2s
Aplant with dark red flowers is crossed with a plant with white flowers. all of the offspring have dark red flowers with white spots. the alleles got flower color in this plant are both dominant both recessive codominant incompletely dominant
Answers: 1
Biology, 22.06.2019 19:30, wolfiewolffromsketch
Forensic scientists think they know the identity of a skeleton. what rule should they use to select a relative whose dna could be used to try to confirm the identity?
Answers: 3
When epidermal growth factor (EGF)—the ligand for the epidermal growth factor receptor (EGFR)—binds...
Social Studies, 12.01.2021 23:40
Chemistry, 12.01.2021 23:40
Mathematics, 12.01.2021 23:40
Law, 12.01.2021 23:40