1. distinguish between different types of mutations 2. explain why mutations may or may not affect phenotype 3. identify internal and external factors that regulate cell division 4.explain cancer in terms of the cell cycle

1.)The types of mutations include: Missense mutation: This type of mutation is a change in one DNA base pair that results in the substitution of one amino acid for another in the protein made by a gene. Nonsense mutation: A nonsense mutation is also a change in one DNA base pair

.2.) Some mutations don't have any noticeable effect on the phenotype of an organism. This can happen in many situations: perhaps the mutation occurs in a stretch of DNA with no function, or perhaps the mutation occurs in a protein-coding region, but ends up not affecting the amino acid sequence of the protein.

3.)External factors include physical and chemical signals. Growth factors are proteins that stimulate cell division. – Most mammal cells form a single layer in a culture dish and stop dividing once they touch other cells. Two of the most important internal factors are kinases and cyclins.

4.) In normal cells, the cell cycle is controlled by a complex series of signaling pathways by which a cell grows, replicates its DNA and divides. ... In cancer, as a result of genetic mutations, this regulatory process malfunctions, resulting in uncontrolled cell proliferation.

Explanation:

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identify the dna change shown in the diagram and explain how that change can result in the increased genetic diversity often seen among siblings.