The complex metabolic pathways in the parasite Trypanosoma brucei (the causative agent of sleeping sickness) were elucidated in part by adding radiolabeled metabolites to cultured parasites. In the parasite, glucose is converted to phosphoenolpyruvate (PEP) in the cytosol. PEP then enters an organelle called the glycosome and is converted to oxaloacetate (OAA); OAA is then converted to malate, and malate to fumarate. Fumarate reductase catalyzes the conversion of fumarate to succinate; the succinate is then secreted from the glycosome. If C1 of glucose is labeled, what carbons in succinate are labeled

Awoman whose sister tested positive for a specific mutation in the brca1 gene, which increases the risk for breast and ovarian cancer, is found not to have that mutation but does have a mutation of unknown significance near the known mutation site. how should this woman be counseled? select one: a. she should be informed that her risk for breast cancer is greater than the general population but not as great as her sister’s risk. b. she should be informed that because she does not have the mutation, her risk for breast cancer is not greater than that of the general population. c. she should be informed of her gene mutation status and be presented with all the available prophylaxis options and reconstruction options. d. she should be informed that she does not have the specific mutation but that because another mutation is present she should be vigilant about screening

A60-tooth gear is connected to a 72-tooth gear. if the smaller gear turns 12 times, how many turns does the larger gear make?

What makes a dominant allele different from a recessive allele